SPIRE2 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-10847

Overview

Synonyms MGC117166,Protein spire homolog 2,Spir-2,SPIR2,Spire homolog 2 (Drosophila),SPIRE2
Swissprot Q8WWL2
Source Rabbit
Reactivity Human
Immunogen Recombinant protein of human SPIRE2
Application IHC,ELISA
Recommended dilution IHC 1:25-1:100
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background SPIRE2, is a 714 amino acid protein belonging to the spire family.  Acts as an actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.

 

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