Overview
| Synonyms | Dihydroxyacetone transferase,EC 2.2.1.2,EPS8L2,Glycerone transferase,TAL,TAL H,TALDO,TALDO,TALDO1,TALDOR,TALH,Transaldolase 1,Transaldolase |
| Swissprot | P37837 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human TALDO1 |
| Application | WB,IHC,ELISA |
| Recommended dilution | WB 1:500-2000, IHC 1:25-100, ELISA 1:2000-5000 |
| Concentration | 0.4mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | |
| Tissue specificity | |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. |
