TBK1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-60743

Overview

Synonyms EC 2.7.11.1,FLJ11330,FTDALS4,NAK,NF kappa B activating kinase,NF kB activating kinase,NF-kappa-B-activating kinase,Serine/threonine protein kinase TBK 1,Serine/threonine protein kinase TBK1,Serine/threonine-protein kinase TBK1,T2K,TANK binding kinase 1,TANK-binding kinase 1,TBK 1,Tbk1,TBK1
Swissprot Q9UHD2
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human TBK1
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

 

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