TCAP Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64719

Overview

Synonyms 19 kDa sarcomeric protein ,CMD1N,CMH25,LGMD2G,Limb girdle muscular dystrophy 2G (autosomal recessive) ,T-cap,Tcap,TELE,Telethonin,TELT,Titin cap protein,Titin-cap
Swissprot O15273
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human TCAP
Application WB,IF
Recommended dilution WB 1:500 - 1:2000 IF 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G.

 

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