TJP2 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63001

Overview

Synonyms C9DUPq21.11,DFNA51,DUP9q21.11,Friedreich ataxia region gene X104 (tight junction protein ZO-2),MGC26306 ,PFIC4,Tight junction protein 2,Tight junction protein ZO 2,Tight junction protein ZO-2,TJP2,X104,ZO 2,ZO-2,ZO2,ZO2,Zona occludens 2,Zona occludens protein 2,Zonula occludens protein 2
Swissprot Q9UDY2
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human TJP2
Application WB,IHC
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene.

 

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