TLR9 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-70125

Overview

Synonyms CD289,TLR 9,TLR9,Toll like receptor 9,Toll like receptor 9 isoform A precursor,Toll like receptor 9 isoform B,Toll-like receptor 9
Swissprot Q9EQU3,Q9NR96
Source Rabbit
Reactivity Human,Mouse
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse TLR9
Application IHC
Recommended dilution IHC 1:100-1:500
Concentration 1.5 mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
Background The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

 

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