TNFRSF10B Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-15602

Overview

Synonyms Fas like protein,Apoptosis inducing protein TRICK2A/2B,Apoptosis inducing receptor TRAIL R2,CD262,CD262 antigen,Cytotoxic TRAIL receptor 2,Death domain containing receptor for TRAIL/Apo 2L,Death receptor 5,DR5,KILLER,KILLER/DR5,OTTHUMP00000123492,OTTHUMP00000123493,p53 regulated DNA damage inducible cell death receptor(killer),TNF related apoptosis inducing ligand receptor 2,TNF-related apoptosis-inducing ligand receptor 2,TNFRSF10B,TR10B,TRAIL R2,TRAIL receptor 2,TRAIL-R2,TRAILR2,TRICK2,TRICK2A,TRICK2B,TRICKB,Tumor necrosis factor receptor like protein ZTNFR9,Tumor necrosis factor receptor superfamily member 10B,Tumor necrosis factor receptor superfamily,member 10b,ZTNFR9
Swissprot O14763
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human TNFRSF10B
Application WB,ELISA
Recommended dilution WB 1:500-1:2000
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.

 

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