TNFRSF11B Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-70067

Overview

Synonyms MGC29565,OCIF,OPG,Osteoclastogenesis inhibitory factor,Osteoprotegerin,PDB5,TNF receptor superfamily member 11b,TNFRSF 11B,TNFRSF11B,TR 1,TR1,TR11B,Tumor necrosis factor receptor superfamily member 11B
Swissprot O08712,O08727
Source Rabbit
Reactivity Mouse,Rat
Immunogen KLH conjugated Synthetic peptide corresponding to Mouse Osteoprotegerin
Application IHC
Recommended dilution IHC 1:200
Concentration 0.93 mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. 

 

You recently viewed

Clear recently viewed
Print Friendly and PDF