TNFRSF8 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16310

Overview

Synonyms CD 30,CD30,CD30 antigen,CD30L receptor,Cytokine receptor CD30,D1S166E,KI 1,KI 1 antigen,Ki-1 antigen,KI1,Lymphocyte activation antigen CD30,TNFRSF 8,Tnfrsf8,TNR8,Tumor necrosis factor receptor superfamily member 8
Swissprot P28908
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human TNFRSF8
Application IHC,ELISA
Recommended dilution IHC 1:50-1:200
Concentration 0.4mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

 

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