TNFSF11 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-30151

Overview

Synonyms CD254,hRANKL2,ODF,OPGL,OPTB2,Osteoclast differentiation factor,Osteoprotegerin ligand,RANKL,Receptor activator of nuclear factor kappa B ligand,Receptor activator of nuclear factor kappa-B ligand,sOdf,TNF related activation induced cytokine,TNF-related activation-induced cytokine,TNF11,TNFSF 11,Tnfsf11,TRANCE,Tumor necrosis factor (ligand) superfamily member 11,Tumor necrosis factor ligand superfamily member 11,Tumor necrosis factor ligand superfamily member 11,soluble form
Swissprot O14788
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the C-terminal region of human RANKL.
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000-1:20000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy.

 

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