TNS1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-33069

Overview

Synonyms matrix-remodelling associated 6,Matrix-remodelling-associated protein 6,MGC88584,MST091,MST122,MST127,MSTP091,MSTP122,MSTP127,MXRA6,TENS1,Tensin,Tensin-1,TNS,TNS1
Swissprot Q9HBL0
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthesized peptide derived from human Tensin-1 around the non-phosphorylation site of Tyr1326.
Application WB,ELISA
Recommended dilution WB 1:500-1:2000, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Background The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.TNS1 (Tensin 1) is a Protein Coding gene. Diseases associated with TNS1 include Bannayan-Riley-Ruvalcaba Syndrome and Ruvalcaba Syndrome. Among its related pathways are Focal Adhesion and Integrin Pathway. GO annotations related to this gene include poly(A) RNA binding and actin binding. An important paralog of this gene is TNS3.

 

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