TPM3 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64714

Overview

Synonyms Alpha tropomyosin 3,Alpha tropomyosin slow skeletal,CFTD,Cytoskeletal tropomyosin TM30,FLJ41118,gamma TM,Gamma tropomyosin,Gamma-tropomyosin,Heat stable cytoskeletal protein 30 kDa,hscp30,hTM30nm,hTM5,hTMnm,MGC102590,MGC14582,MGC3261,MGC72094,NEM1,OK/SW-cl.5,OTTHUMP00000034019,OTTHUMP00000034171,OTTHUMP00000034172,TM 5,TM-5,TM3,TM30,TM30nm,TM5,Tm5NM,Tpm 5,TPM3,TPM3/NTRK1 FUSION GENE,INCLUDED,TPM3,Tpm5,TPMsk3,TRK,TRK ONCOGENE,INCLUDED,Trop 5,Tropomyosin 3,Tropomyosin 3 gamma,Tropomyosin 5,Tropomyosin alpha 3 chain,Tropomyosin alpha-3 chain,Tropomyosin gamma,Tropomyosin-3,Tropomyosin-5
Swissprot P06753
Source Rabbit
Reactivity Mouse
Immunogen Recombinant protein of human TPM3
Application WB,IHC
Recommended dilution WB 1:500 - 1:2000 IHC 1:50 - 1:200
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.

 

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