TRIM74 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-17151

Overview

Synonyms MGC45440,TRI74,TRIM 74,TRIM74,Tripartite motif containing 50C,Tripartite motif containing 74,Tripartite motif containing protein 50C,Tripartite motif containing protein 74,Tripartite motif-containing protein 50C,Tripartite motif-containing protein 74
Swissprot Q86UV6
Source Rabbit
Reactivity Human
Immunogen Full length fusion protein
Application IHC,ELISA
Recommended dilution IHC 1:30-150, ELISA 1:2000-10000
Concentration 1.1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background TRIM 74 (Tripartite motif-containing protein 74) is a possible protein coding regions found at gene location 7q11.23. Tripartite motif (TRIM) proteins play important roles in a variety of cellular functions including cell proliferation, differentiation, development, oncogenesis, and apoptosis. TRIM gene expression analysis in primary human immune cells seem to suggest the involvement of TRIM proteins in also regulating host antiviral activities. The gene encoding TRIM 74 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.

 

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