TRPM5 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-12915

Overview

Synonyms 9430099A16Rik,Long transient receptor potential channel 5,LTrpC-5,LTrpC5,MLSN1 and TRP related gene 1,MLSN1 and TRP related gene 1 protein,MLSN1 and TRP-related,MLSN1- and TRP-related gene 1 protein,MTR1,Novel protein similar to vertebrate transient receptor potential cation channel,subfamily M,member 5,Transient receptor potential cation channel subfamily M member 5,Transient receptor potential cation channel,subfamily M,member 5,Trpm5,TRPM5 transient receptor potential cation channel,subfamily M,member 5,TRPM5
Swissprot Q9NZQ8
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human TRPM5
Application WB,IHC,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:50-1:200
Concentration 0.6mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.

 

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