TSHB Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-61360

Overview

Synonyms CHNG4,Thyroid stimulating hormone beta subunit,Thyroid stimulating hormone,beta precursor,Thyrotropin beta subunit,TSHB
Swissprot P01222
Source Rabbit
Reactivity Human,Mouse
Immunogen Recombinant protein of human TSHB
Application IHC,IF
Recommended dilution IHC 1:50 - 1:100 IF 1:50 - 1:100
Concentration 1mg/ml
Clonality Polyclonal

 

Properties

Cellular localization Secreted
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze/thaw cycles.
Storage buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of the thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.

 

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