Overview
| Synonyms | homolog of C. elegans transmembrane receptor Unc5 ,Netrin receptor UNC5C,Protein unc 5 homolog C,Protein unc-5 homolog 3,Protein unc-5 homolog C,Unc 5 homolog 3,Unc 5 homolog C,Unc5 (C.elegans homolog) c ,Unc5c,UNC5C,UNC5H3 |
| Swissprot | O95185 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human UNC5C |
| Application | WB |
| Recommended dilution | WB 1:500 - 1:2000 |
| Concentration | 1mg/ml |
| Clonality | Polyclonal |
Properties
| Cellular localization | |
| Tissue specificity | |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Background | This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. |
