UNC5C Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-65114

Overview

Synonyms homolog of C. elegans transmembrane receptor Unc5 ,Netrin receptor UNC5C,Protein unc 5 homolog C,Protein unc-5 homolog 3,Protein unc-5 homolog C,Unc 5 homolog 3,Unc 5 homolog C,Unc5 (C.elegans homolog) c ,Unc5c,UNC5C,UNC5H3
Swissprot O95185
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human UNC5C
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region.

 

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