UQCRB Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-62256

Overview

Synonyms Complex III subunit 7,Complex III subunit VII,Cytochrome b-c1 complex subunit 7,MC3DN3,Mitochondrial ubiquinone-binding protein,QCR7,QCR7,QP-C,QPC,Ubiquinol cytochrome c reductase complex III subunit VI,Ubiquinol-cytochrome c reductase binding protein,Ubiquinol-cytochrome c reductase complex 14 kDa protein,Ubiquinone-binding protein,UQBC,UQBP,UQCR6,UQCRB,UQPC
Swissprot P14927
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human UQCRB
Application WB
Recommended dilution WB 1:1000 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a subunit of the ubiquinol-cytochrome c oxidoreductase complex, which consists of one mitochondrial-encoded and 10 nuclear-encoded subunits. The protein encoded by this gene binds ubiquinone and participates in the transfer of electrons when ubiquinone is bound. This protein plays an important role in hypoxia-induced angiogenesis through mitochondrial reactive oxygen species-mediated signaling. Mutations in this gene are associated with mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. Related pseudogenes have been identified on chromosomes 1, 5 and X.

 

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