VPS72 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-35474

Overview

Synonyms CFL1,HGNC11644,Protein YL-1,Swc2,TCFL1,Transcription factor like 1 (YL1),Transcription Factor Like 1,Transcription factor-like 1,Vacuolar protein sorting 72 (yeast),Vacuolar protein sorting 72 homolog (S. cerevisiae),Vacuolar protein sorting associated protein 72 homolog,Vacuolar protein sorting-associated protein 72 homolog,VPS72,VPS72,YL-1,YL1
Swissprot Q15906
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthesized peptide derived from the Internal region of human VPS72
Application WB,IHC-p,IF,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background VPS72 (Vacuolar Protein Sorting 72 Homolog) is a Protein Coding gene. Among its related pathways are Chromatin organization.The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

 

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