WDR11 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63449

Overview

Synonyms Bromodomain and WD repeat containing protein 2,Bromodomain and WD repeat domain containing 2,Bromodomain- and WD repeat-containing protein 2, formerly,BRWD2,BRWD2, formerly,DKFZp434L1715,DR11,FLJ42531,HH14,KIAA1351,WD repeat containing protein 11,WD repeat containing protein 15,WD repeat domain 11,WD repeat domain 15,WDR 11,WDR15
Swissprot Q9BZH6
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human WDR11
Application WB
Recommended dilution WB 1:1000 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.

 

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