XPO1 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-63247

Overview

Synonyms Chromosome region maintenance 1 protein homolog,CRM 1,CRM1 homolog,DKFZp686B1823,emb,Exp 1,Exp1,Exportin 1,Exportin-1,Exportin1,XPO 1,xpo1,XPO1
Swissprot O14980
Source Rabbit
Reactivity Human,Mouse
Immunogen A synthetic peptide of human XPO1
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Background This cell-cycle-regulated gene encodes a protein that mediates leucine-rich nuclear export signal (NES)-dependent protein transport. The protein specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1.

 

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