ZFP36L1 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-33110

Overview

Synonyms Berg36,BRF1,Butyrate response factor 1,C3H1 type-like 1,cMG1,EGF-response factor 1,ERF-1,ERF1,Protein TIS11B,RNF162B,TIS11B,TISB,ZFP36L1,Zinc finger protein 36
Swissprot Q07352
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from human TIS11B around the non-phosphorylation site of S92.
Application WB,IHC-p,ELISA
Recommended dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
Concentration 1mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4.
Background This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.ZFP36L1 (ZFP36 Ring Finger Protein Like 1) is a Protein Coding gene. Diseases associated with ZFP36L1 include Sotos Syndrome 1. Among its related pathways are Validated targets of C-MYC transcriptional repression and PI3K / Akt Signaling. GO annotations related to this gene include poly(A) RNA binding and mRNA binding. An important paralog of this gene is ZFP36L2.

 

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