ZFP42 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-16185

Overview

Synonyms hREX-1,Reduced Expression 1 Protein,Reduced expression protein 1,Rex-1,REX1,REX1 transcription factor,Zfp-42,Zfp42,ZFP42 zinc finger protein,ZFP42,Zinc finger protein 42 homolog,Zinc finger protein 754,ZNF754
Swissprot Q96MM3
Source Rabbit
Reactivity Human
Immunogen Synthetic peptide of human ZFP42
Application WB,ELISA
Recommended dilution WB 1:200-1:1000
Concentration 0.2mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.

 

You recently viewed

Clear recently viewed
Print Friendly and PDF