ZNF281 Polyclonal Antibody

Rs. 16,500.00
SKU E-AB-17643

Overview

Synonyms GC box binding zinc finger protein 1,GC-box-binding zinc finger protein 1,GZP1,Transcription factor ZBP-99,ZBP 99,ZBP99,zfp281,Zinc finger DNA binding protein 99,Zinc finger DNA-binding protein 99,Zinc finger protein 281,ZN281,ZNF281,ZNP 99,ZNP 99 transcription factor,ZNP99
Swissprot Q9Y2X9
Source Rabbit
Reactivity Human,Mouse
Immunogen Synthetic peptide of human ZNF281
Application IHC,ELISA
Recommended dilution IHC 1:25-100, ELISA 1:2000-5000
Concentration 0.3mg/mL
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Storage buffer PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Background ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR.

 

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