ZNF346 Polyclonal Antibody

Rs. 21,832.00
SKU E-AB-64617

Overview

Synonyms DKFZp547M223,Double stranded RNA binding zinc finger protein ,Double stranded RNA binding zinc finger protein JAZ,JAZ,Just another zinc finger protein,Zfp346,Zinc finger protein 346,ZN346,Znf346
Swissprot Q9UL40
Source Rabbit
Reactivity Human,Mouse,Rat
Immunogen Recombinant protein of human ZNF346
Application WB
Recommended dilution WB 1:500 - 1:2000
Concentration 1mg/ml
Clonality Polyclonal

Properties

Cellular localization  
Tissue specificity  
Isotype IgG
Purification Affinity purification
Conjugation Unconjugated
Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage buffer
Background The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. It plays a role in protecting neurons by inhibiting cell cycle re-entry via stimulation of p21 gene expression. Alternative splicing of this gene results in multiple transcript variants.

 

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